|
Datasheet
Virbamec Super
Injectable solution for Cattle
Presentation
A sterile, non-aqueous solution for subcutaneous injection.
Each ml contains:
Ivermectin…………………..10mg
Clorsulon……………………100mg
Uses
Cattle
For the treatment and control of the following species of gastro-intestinal
roundworms, lungworms, liver fluke, eyeworms, warbles, mites and lice
of cattle:
Gastro-intestinal roundworms
(adult and fourth-stage larvae):
Ostertagia ostertagi (including inhibited O. ostertagi)
Ostertagia lyrata
Haemonchus placei
Trichostrongylus axei
Trichostrongylus colubriformis
Cooperia onchophora
Cooperia punctata
Cooperia pectinata
Bunostomum phlebotomum
Oesophagostomum radiatum
Strongyloides papillosus (adult)
Nematodirus helvetianus (adult)
Nematodirus spathiger (adult)
Trichuris spp. (adult)
Lungworms (adult
and fourth stage larvae):
Dictyocaulus viviparus
Liver fluke
(adult):
Fasciola hepatica
Eyeworms (adult):
Thelazia spp.
Warbles:
Hypoderma bovis
Hypoderma lineatum
Mange mites:
Psoroptes bovis
Sarcoptes scabei var. bovis
Sucking lice:
Linognathus vituli
Haematopinus eurysternus
Solenopotes capillatus.
Virbamec Super may also be used as an aid in the control of the biting
louse Damalinia bovis and the mange mite Chorioptes bovis,
but complete elimination may not occur.
Persistent activity:
When cattle have to graze on pasture contaminated with infective larvae
of cattle nematodes, treatment with Virbamec Super at the recommended
dose rate controls re-infection with Cooperia spp., Haemonchus placei
and Trichostrongylus axei acquired up to 14 days after treatment, Ostertagia
ostertagi and Oesophagostomum radiatum acquired up to
21 days and Dictyocaulus viviparus acquired up to 28 days after
treatment.
The product contains ivermectin and clorsulon. Studies have shown that
first-season grazing calves turned out to pasture in late April or May
and treated with ivermectin 3, 8 and 13 weeks after turnout can be protected
from parasitic gastro-enteritis and lungworm disease throughout the grazing
season, provided they are set-stocked, all calves are included in the
programme and that no untreated cattle are added to the pasture. The product
can be used 3, 8 and 13 weeks after the day of turnout only if chronic
fluke or the threat of chronic fluke is present in the cattle to be treated.
Treated animals should always be monitored
according to good husbandry practices.
Dosage and administration
Cattle
Virbamec Super should be given only by subcutaneous injection at the recommended
dosage level of 200 mcg ivermectin per kilogram bodyweight and 2mg clorsulon
per kilogram bodyweight. Each ml contains 10 mg of ivermectin and 100mg
clorsulon, sufficient to treat 50kg of bodyweight.
Dosage schedule
| Bodyweight
(kg) |
Dose
Volume (ml) |
| Up to 50 |
1.0 |
| 51 – 100 |
2.0 |
| 151 – 150 |
3.0 |
| 201 – 200 |
4.0 |
| 251 – 250 |
5.0 |
| 301 – 300 |
6.0 |
| 351 – 350 |
7.0 |
| 401 – 400 |
8.0 |
| 101 – 450 |
9.0 |
| 451 – 500 |
10.0 |
| 501 – 550 |
11.0 |
| 551 – 600 |
12.0 |
Use a dry sterile needle. Divide doses greater
than 10ml between two injection sites. Inject under the loose skin in front
of or behind the shoulder. Use of 17 gauge ½ inch (15-20mm) needle
is suggested. The injection may be given with any standard automatic, multidose
or single dose hypodermic syringe. If using a single-dose or hypodermic
syringe, use a separate sterile needle to withdraw the product from the
pack. This product does not contain an antimicrobial preservative. Swab
septum before remoing each dose. For 200, 500 and 1000 ml pack sizes, use
of a multiple dose automatic syringe is recommended. To refill the syringe,
use of a draw-off needle is recommended to avoid excessive broaching of
the stopper. When the temperature of the product is below 5°C, difficulty
in administration may be encountered due to increased viscosity. Warming
the product and injection equipment to about 15°C will greatly increase
the ease with which the product can be injected. Different injection sites
should be used for other parenteral products.
Withdrawal Period Information
| Cattle Milk |
Cattle Meat |
Sheep Meat |
Pig Meat |
Poultry Meat |
Poultry Eggs |
Fish Meat |
Notes |
| - |
80 days |
- |
- |
- |
- |
- |
Do not use within 60 days calving/Not for use in cows producing
milk
for human consumption |
Contra-indications, warnings, etc
For animal treatment only. This product should not be used intravenously
or intramuscularly.
Do not use in cattle producing milk for human consumption.
Do not use in non-lactating dairy cows including pregnant heifers within
60 days of calving.
Do not use in species other than cattle as severe adverse reactions, including
fatalities in dogs, may occur.
Operator warnings
Do not smoke or eat whilst handling the product. Wash hands after use.
Take care to avoid self-administration: the product may cause irritation
and/or pain at the site of injection.
Withdrawal period
Cattle
Cattle must not be treated within 80 days of slaughter for human consumption.
Do not use in cattle producing milk for human consumption. Do not use
in non-lactating dairy cows including pregnant heifers within 60 days
of calving.
Disposal of containers
Unused product and containers should be disposed of in accordance with
any guidance from an appropriate waste regulation authority.
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface
waters or ditches with product or used product container.
Pharmaceutical precautions
This product does not contain an antimicrobial preservative, therefore
the stopper should be swabbed before removing each dose. Use a dry, sterile
needle and syringe. Store below 25°C. Following withdrawal of the
first dose, use the product within 28 days. Discard unused material. Avoid
introduction of contamination. Protect from light.
Legal category
POM-VPS formerly PML
Package quantities
50 ml, 200 ml, 500 ml and 1000ml multidose, colourless, plastic vials.
Further information
Studies have shown a wide safety margin and at the recommended dosage,
no adverse effects on breeding performance were observed. At therapeutic
doses, ivermectin has no adverse effect on cattle since it does not readily
penetrate the bovine central nervous system. Transient discomfort has
been observed in some cattle following subcutaneous administration.
A low incidence of soft tissue swelling at the injection site has been
observed. These reactions have disappeared without treatment.
Ivermectin is a highly active, broad spectrum, internal and external parasiticide
of the avermectin family.
Ivermectins are isolated after fermentation of the soil organism Streptomyces
avermitilis. Ivermectin stimulates the release of gamma amino butyric
acid (GABA) at presynaptic nerve terminals (in nematodes) or the neuromuscular
junctions (in arthropods, acarids, flies and fleas), leading to the paralysis
and death of the parasite concerned.
Clorsulon inhibits glycolytic enzymes of Fasciola hepatica. This
enzymatic inhibition effectively blocks the Embden-Myerhof glycolytic
pathway and thereby deprives the fluke of its main source of metabolic
energy.
Market Authorisation number
Vm 16971/4010
Distributed by
Virbac Ltd, Woolpit Business Park, Windmill Avenue, Woolpit, Suffolk.
IP30 9UP
Marketing authorisation holder
VIRBAC DE PORTUGAL LABORATORIOS LDA, Rua Duonisio Saraiva, Lote 1, 1°
Andar, Sala 2, 2080 Almeirim – PORTUGAL
|
